دانشگاه علوم پزشکی ایران
Iran University of Medical Sciences

دکتر اعظم حسین زاده

 | تاریخ ارسال: ۱۳۹۷/۳/۷ | 
      نام: اعظم

      نام خانوادگی: حسین زاده

      سمت: هیئت علمی

      رتبه علمی: استادیار

      آخرین مدرک تحصیلی: دکتری

     گرایش: فارماکولوژی

     ایمیل: Hoseinzadeh.a@iums.ac.ir
                 azam.hosseinzade@yahoo.com 

     شماره تماس: 86703134

·Research Interests:

  •  Molecular medicine
  • Molecular pharmacology and toxicology
  • Clinical studies
  • Pulmonary fibrosis
  • Diabetes
  • Regenerative medicine
  • Herbal medicine
 

·Work and Education

  • 2018-Present: Assistant Professor, Razi Drug Research Center,   Iran University of Medical Sciences, Tehran, Iran
  • 2011-2017:Ph.D Pharmacology, Iran University of Medical Sciences
  • 2003-2010: DVM Veterinary Medicine, Tehran University

·Publications

              
  • Hosseinzadeh A, Kamrava SK, Joghataei MT, Darabi R, Shakeri‐Zadeh A, Shahriari M, et al. Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin. Journal of pineal research 2016.
 
  • Hosseinzadeh A, Jafari D, Kamarul T, Bagheri A, Sharifi AM. Evaluating the Protective Effects and Mechanisms of Diallyl Disulfide on Interlukin‐1β‐Induced Oxidative Stress and Mitochondrial Apoptotic Signaling Pathways in Cultured Chondrocytes. Journal of Cellular Biochemistry 2017; 118: 1879-1888.
   
  • Hosseinzadeh A, Juybari KB, Fatemi MJ, Kamarul T, Bagheri A, Tekiyehmaroof N, et al. Protective Effect of Ginger (Zingiber officinale Roscoe) Extract against Oxidative Stress and Mitochondrial Apoptosis Induced by Interleukin-1β in Cultured Chondrocytes. Cells Tissues Organs 2017.
 
  • E Dehdashtian, S Mehrzadi, B Yousefi, M Safa, A Hosseinzadeh, R J. Reiter, Habib Ghaznavi, M Naseripour. Melatonin Ameliorates Diabetic Retinopathy:
    Involvement of Autophagy, Inflammation and Antioxidative Processes. Life science.
   
  • Daryani A, Montazeri M, Pagheh A, Sharif M, Sarvi S, Hosseinzadeh A, et al. The potential use of melatonin to treat protozoan parasitic infections: A review. Biomedicine & pharmacotherapy= Biomedecine & pharmacotherapie 2017; 97: 948.
 
  • Javad-Mousavi SA, Hemmati AA, Mehrzadi S, Hosseinzadeh A, Houshmand G, Nooshabadi MRR, et al. Protective effect of Berberis vulgaris fruit extract against Paraquat-induced pulmonary fibrosis in rats. Biomedicine & Pharmacotherapy 2016; 81: 329-336.
 
  • Mehrzadi S, Kamrava SK, Dormanesh B, Motevalian M, Hosseinzadeh A, Hosseini Tabatabaei SMT, et al. Melatonin synergistically enhances protective effect of atorvastatin against gentamicin-induced nephrotoxicity in rat kidney. Canadian journal of physiology and pharmacology 2015; 94: 265-271.
 
  • Mehrzadi S, Sadr S, Hosseinzadeh A, Gholamine B, Shahbazi A, FallahHuseini H, et al. Anticonvulsant activity of the ethanolic extract of Punica granatum L. seed. Neurological research 2015; 37: 470-475.
 
  • Safaei F, Mehrzadi S, Khadem Haghighian H, Hosseinzadeh A, Nesari A, Dolatshahi M, et al. Protective effects of gallic acid against methotrexate-induced toxicity in rats. Acta Chirurgica Belgica 2017: 1-9.
 
  • Ghaznavi H, Mehrzadi S, Dormanesh B, Tabatabaei SMTH, Vahedi H, Hosseinzadeh A, et al. Comparison of the protective effects of melatonin and silymarin against gentamicin-induced nephrotoxicity in rats. Journal of evidence-based complementary & alternative medicine 2016; 21: NP49-NP55
 

-A HosseinzadehT MohajerfarA Akhondzadeh Basti A Khanjari, et al. Determination of minimum inhibitory concentration (MIC) of Zataria multiflora Boiss. essential oil and lysozim on E. coli 0157: H7. Journal of Medicinal Plants

   

·Conference papers

 
 

-The physicochemical properties of fetal bovine serum proteins can be affected by gamma-irradiation.

  • Anticonvulsant activity of the ethanolic extract of Punica granatum L. seed
  • Protective effect of Berberis vulgaris fruit extract against Paraquat-induced pulmonary fibrosis in rats
 

·Collaboration in research projects

 
  • Evaluating the Protective Effects and Mechanisms of Diallyl Disulfide on Interlukin-1b-Induced Oxidative Stress and Mitochondrial Apoptotic Signaling Pathways in Cultured Chondrocytes.
  • Investigating the effect of garlic organosulfur compound (diallyl disulfide) on antioxidants gene and protein expression in cultured cartilage cells exposed to inflammatory cytokines.
  • Investigation of the effect of Gold-coated iron oxide nanoparticles in the presence of laser on CT26 colon tumor bearing Balb/c mice.
  • Evaluation of atorvastatin effects against glucose induced injury through inhibition of oxidative stress and apoptotic signaling pathway in cultured chondrocytes.
  • Protective Effect of Ginger ( Zingiber officinale Roscoe) Extract against Oxidative Stress and Mitochondrial Apoptosis Induced by Interleukin-1β in Cultured Chondrocytes.

·Participation in Workshops

  • Microbial resistance of skin diseases against antibiotics, Tehran University of Medical Sciences Tehran, Iran, 2011.
  • Teaching methods, Iran University of Medical Sciences, Tehran, Iran, 2014.
  • Academic writing (advanced), Tehran University of Medical Sciences, Tehran, Iran, 2017.
  • Introduction to the drug discovery and formulation, Iran University of Medical Sciences, Tehran, Iran, 2018.
  • RCT-GCP Workshop, National Institute for Medical Research Development (NIMAD), Tehran, Iran, 2018.

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